Monday, March, 18, 2019 06:37:35

Applications- Immunoprecipitation, Antibody Purification drives the growth of Protein A Resins Market

The Protein A Resins Market is set to exceed USD 900 million by 2024; according to a new research report by Global Market Insights.

Protein A Resins Market on the basis of Applications:

Immunoprecipitation application segment of protein A resins market is forecasted to witness robust growth rate over forthcoming years. Immunoprecipitation is widely applicable in research and development sector. As protein A resins are used in immunoprecipitation technique its demand is forecasted to go hand in hand with increasing demand for immunoprecipitation.

Antibody purification segment of protein A resins market accounted for largest revenue share in 2017 and is forecasted to continue to dominate the industry in near future. The increasing demand for therapeutic antibodies and high research and development activities in the antibody field will escalate the segment growth to some extent.

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Recombinant protein A resins segment of protein A resins market dominated the industry over forecast timeframe. Recombinant protein A is formulated in E.Coli and functions same as that of natural protein A resins. However, recombinant form of protein is preferred where other production source offers less non-specific binding.

Natural protein A resins provides high capacity antibody purification but are sensitive to alkaline conditions. Due to sensitivity to alkaline conditions, cleaning in place (CIP) of natural a protein resins with 0.1M or 1M NaOH is not feasible. Thus, alternative CIP must be used that in turns increase the overall cost of procedure.

Glass or silica gel-based matrix segment of protein A resins market is forecasted to witness healthy growth over the forecast timeframe due to improved durability, mechanical strength and ability to incorporate high absorption of metallic dopants.

However, agarose-based matrix type accounted for largest revenue share in 2017 and is expected to dominate the industry throughout the forecast period. Suitable pH range, good resolution at minimum time, high flow rate makes these types of beads perfect for process scale practices.

U.S. accounted for largest regional share in 2017 due to robust research and development in the field of drug discovery and ongoing inflow of approved monoclonal antibodies in the protein A resins market. Technological advancements coupled with the availability of funding for research on novel therapies will further render significant positive impact growth.

Japan protein A resins market dominated the Asia Pacific region in 2017 due to increasing demand for novel therapies to combat with chronic diseases. Well-developed pharmaceutical sector and healthcare infrastructure, and ongoing research and development activities will augment Japanese protein A resins market.

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Some of the key industry players operating in global protein A resin market are Agarose Bead Technologies (ABT), Bio-Rad Laboratories, Danaher Corporation, EMD Millipore, Expedeon, GE Healthcare, GenScript Corporation, Novasep, Repligen, Sigma-Aldrich Corporation, Takara Bio, Thermo Fisher Scientific, Tosoh Bioscience. The industry players are focusing on new product development for strengthening their position and broaden their product portfolio. For instance, in September 2017, GE healthcare launched MabSelect PrismA, a new protein A chromatography resin for capturing monoclonal antibodies.